The European Medical Agency (EMA) has issued a draft guideline on the quality and equivalence of topical products.The equivalence for complex semisolid formulations involves several steps: the same quantitative content, the same microstructure, the same release, and Doll permeation profile.In this paper, several batches of a low strength topical pr
A number of stellar astrophysical phenomena, such as tidal novae and planetary engulfment, involve sudden injection of subbinding energy in a thin layer within the star, leading to mass ejection of the stellar envelope.We use a 1D hydrodynamical model Tomato to survey the stellar response and mass loss for various amounts ( E _dep ) and locations o
Halal is a crucial concept for Muslim consumers regarding consumed products, including pharmaceutical ingredients, which are essential in modern medicine.To address the issue of using porcine-sourced ingredients in pharmaceuticals, it is essential to search for halal alternatives derived from poultry, Tomato animal by-products from meat processing,
Objective: to study the current state of the legislative regulation of nicotine-containing products turnover and consumption; to identify the main problems in this area and to suggest possible ways to solve them.Methods: the methodological basis of the work is interdisciplinary, systematic and comparative approaches, as well as general scientific m